Pioneering Women of Physics
Pioneering Women of Physics
(by Perimeter Institute for Theoretical Physics)
Pioneering Women of Physics
(by Perimeter Institute for Theoretical Physics)
Pioneering Women of Physics
(by Perimeter Institute for Theoretical Physics)
Pioneering Women of Physics
(by Perimeter Institute for Theoretical Physics)
What a piece of work is ARHGAP11B, how noble in reason, how infinite in faculty!
Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion
by Wieland B. Huttner, Marta Florio, Mareike Albert, et al.
Science DOI: 10.1126/science.aaa1975
Published Online February 26 2015
Evolutionary expansion of the human neocortex reflects increased amplification of basal progenitors in the subventricular zone, producing more neurons during fetal corticogenesis. Here, we analyze the transcriptomes of distinct progenitor subpopulations isolated by a cell polarity-based approach from developing mouse and human neocortex. We identify 56 genes preferentially expressed in human apical and basal radial glia that lack mouse orthologs. Among these, ARHGAP11B has the highest degree of radial glia-specific expression. ARHGAP11B arose from partial duplication of the Rho GTPase-activating-protein–encoding ARHGAP11A on the human lineage after separation from the chimpanzee lineage. Expression of ARHGAP11B in embryonic mouse neocortex promotes basal progenitor generation and self-renewal, and can increase cortical plate area and induce gyrification. Hence, ARHGAP11B may have contributed to evolutionary expansion of human neocortex. Read More »
The smallest life-form on Earth
This cryo-electron tomography image reveals the internal structure of an ultra-small bacteria cell like never before. The cell has a very dense interior compartment and a complex cell wall. The darker spots at each end of the cell are most likely ribosomes. The image was obtained from a 3-D reconstruction. The scale bar is 100 nanometers.
Diverse uncultivated ultra-small bacterial cells in groundwater
by Luis R. Comolli, Jillian F. Banfield et al.
Nature Communications 6, No. 6372, 27 February 2015
doi:10.1038/ncomms7372
Pre-print of Dr. Avijit Roy’s final article for Free Inquiry, to be published in the upcoming April/May issue:
*** “The Virus of Faith” [free PDF-download] ***
The Virus of Faith
by Avijit Roy (1972 - 26 Feb 2015)
Religion, a medieval form of unreason, when combined with modern weaponry becomes a real threat to our freedoms.
—Salman Rushdie
R.I.P. Avijit Roy (murdered 26 February 2015)
R.I.P. Avijit Roy (murdered 26 February 2015)
Author of the blog "Mukto-mona" encouraging freethinking, humanism, and rationalism in Bangladesh (closed by government):
Mukto-mona (Internet Archive, captured 26 Okt 2014)
The entire LHC is built from a total of 371 standard Lego pieces and each model can be put together in less than ten minutes, even by non-physicists:
http://build-your-own-particle-detector.org
Vortex Lamp
by Carlo Crovato.
Adriaen van de Venne (1589-1662)
OpenPetition:
Büchervernichten in Berlin? Bibliotheken werden kaputt rationalisiert
Bitte wenden Sie sich gegen Pläne des Stiftungsrats der Zentral- und Landesbibliothek Berlin, den Medien-Einkauf künftig über den externen privaten Dienstleister EKZ in Reutlingen abwickeln zu lassen statt wie bisher nur über ausgebildetet LektorInnen der Berliner Bibliotheken.
Bitte wenden Sie sich auch gegen die Pläne, Medien, die länger als zwei Jahre nicht ausgeliehen wurden, zu VERNICHTEN.
Bitte wenden Sie sich gegen weitere Vernichtung von Berliner Bibliothekskultur durch Privatisierung, Rationalisierungen und Einsparungen und setzen Sie sich für eine lebendige Bibliothekskultur (nicht nur) in der Hauptstadt ein.
Unterschriftenliste bei OpenPetition offen bis 13.03.2015:
https://www.openpetition.de/petition/online/buechervernichten-in-berlin-bibliotheken-werden-kaputt-rationalisiert Read More »
In spem aeterni consortii
Valentine's Day 2015, Cave of Diros, Peloponnese: Archaeologists have discovered the double burial of a prehistoric couple positioned in an embrace, carbon-dated to 3800 BCE.